PCCM’s mission is to address the unique clinical features and demographic distribution of breast cancer in India. With an emphasis on Triple Negative Breast Cancers (TNBC), prevalent and aggressive in Indian women, our efforts, in conjunction with IISER-Pune, have provided deeper insights into the molecular aspects of various breast cancer subtypes.
Breast cancer is a complex disease with distinct subtypes that respond differently to treatment and have varying prognoses. One such subtype, Triple-Negative Breast Cancer (TNBC), accounts for a higher percentage of cases in India compared to Western populations.
To better understand TNBC and its unique characteristics in the Indian context, PCCM’s CTCR is utilizing many cutting-edge techniques like Multiplex Immunofluorescence (mIF). mIF enables simultaneous analysis of multiple markers in tissue sections, providing insights into specific cell types and their spatial distribution within the tumor microenvironment.
Our Translational cutting-edge research encompasses multiplex TILs analysis, tumor microenvironment analysis, developing AI-ML algorithms with breast cancer digital pathology, and the understanding heritability nature of some breast cancers.
